10 Apr OCEANICURE SC-23PTM CLINICAL GRADE SEA CUCUMBER EXTRACT
Frondosides from Cucumaria frondosa
Few creatures in the world are packed with as many useful and high-value nutrients and bioactive components as the Cucumaria frondosa Sea Cucumber. Like krill and plankton, it is afterall an accumulator of essential nutrients from the ocean. With properties unlike other marine organisms of normal size, the Sea Cucumber has unique composition, morphology, and abilities. Perhaps the most compelling compounds found in the Cucumaria frondosa species of Sea Cucumber are a class of uniquely Sea Cucumber triterpene glycosides known as frondosides and cucumariasides. Some of these compounds play a role in its defense against predators, and are considered toxins to small fishes. But, for humans they have demonstrated to be life saving medicines in their own
right, with Frondoside-A commanding prices among research scientists to the tune of US$23,000,000 per KG and upwards to $67,000,000 per KG from some suppliers. Research in the field is ongoing, with an emphasis on frondosides for cancer treatment and big-pharma vying for their share of the innovation and drug development payout.
Origins
The princpals at Primary Nutrition Inc have been in the Sea Cucumber business for over thirty years. As a primary supplier of this wild caught species, we have witnessed the extensive research that has been conducted over the past seventeen years. We are directly engaged in the fishery, and have invested in the development of proprietary handling, processing, drying, and extraction techniques. Our focus has been in assuring that we can produce a consistent, standardized, clinical grade bioactive material that exceeds all other Sea Cucumber products in quality, potency, and sustainability. Our company is dedicated to bringing you extremely valuable and effective formulations that far outweight their relatively affordable price points.
We are pleased to present to you SC-23P™, a concentrated sea cucumber powder capsule that offers significantly higher levels of key bioactives than traditional Sea Cucumber supplements. Our product is particularly rich in Frondoside A, B, & C; Cucumariasides; Fucosylated Chondroitin Sulfate; Omega 3 Carotenoids, Cerebrosides; and many more compounds that we will be exploring in this newsletter series. We are certain that you will find it highly informative, and ultimately very helpful to your healthcare practice and the wellbeing of your patients and clients if you choose to prescribe and recommend our products as supplements to your treatment protocols.
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So without futher adu let’s explore some of the main points about frondosides.
Scientific Insights into the Health Benefits of Sea Cucumber:
A Focus on Frondosides
In recent years, the burgeoning interest in marine-derived compounds as potential therapeutic agents has significantly increased. Among these, Sea Cucumbers, particularly Cucumaria frondosa, have garnered attention due to their rich profile of bioactive compounds, including Frondosides. This document aims to provide healthcare professionals with an overview of the emerging research surrounding these compounds.
Frodosides have shown significant potential for supporting immune function, enhancing cellular health, and providing anti-inflammatory and anti-cancer effects. Our goal with this newsletter series is to share insights into the clinical relevance of Oceanicure SC-23P™ sea cucumber extract and its most valuable constituents in supporting diverse therapeutic areas.
Frondosides: Structure and Bioactivity
Frondosides are a class of triterpenoid saponins (triterpene glycosides) unique to sea cucumbers. Their complex glycosidic structures contribute to their polar nature, influencing their bioactivity and solubility. Emerging research indicates that these compounds possess a spectrum of beneficial activities and pharmacological properties, including:
- Antitumor / Anti-Cancer Activity: Frondoside A has demonstrated potential in inducing apoptosis in various cancer cell lines, suggesting its role as a natural anticancer agent. Preliminary studies have shown significant reductions in angiogenesis, cell viability, and tumor growth in a broad range of cancers. Researchers suggest that dosing and administration pathways can vary from topical to oral, from intravenous to suppository depending on cancer types and locations.
- Immunomodulatory Effects: Evidence indicates that Frondosides may enhance immune function by promoting the proliferation and activity of immune cells, such as macrophages and T-cells. This modulation could be beneficial in supporting the body’s defense mechanisms against diseases by promoting a balanced immune response.
- Anti-Inflammatory Properties: The bioactive compounds found in sea cucumbers, including Frondosides, have been linked to anti-inflammatory effects. This may provide a complementary approach to managing inflammatory conditions.
- Clinical Implications: Exploration of frondoside benefits in cases of chronic inflammation, autoimmune conditions, and oncology support.
Frondoside A
Current Evidence and Research Highlights
- Mechanisms of Action: Detailed insights into frondoside interactions at the cellular level, specifically their modulation of inflammatory pathways and immune system biomarkers.
- Comparative Efficacy: Summaries of studies comparing frondosides to other naturally occurring compounds known for anti-inflammatory and immunomodulatory effects.
- Results of In-Vivo and In-Vitro Testing: Includes mice, rat, human, and isolated tumors and biochemical research.
- Clinical Implications: Exploration of frondoside benefits in cases of chronic inflammation, autoimmune conditions, and oncology support.
Clinical Relevance & Considerations for Integrating Sea Cucumber Extracts in Patient Care
While the therapeutic potential of Frondosides is still being explored, the preliminary findings present exciting possibilities for incorporation into complementary and integrative medicine. Sea cucumber products could serve as adjuncts in cancer therapy, immune support, and overall health enhancement.
Healthcare professionals are encouraged to consider the role of marine-derived compounds within the broader context of patient care. As the body of evidence grows, these natural products may offer valuable alternatives or supplements to conventional treatments.
Sea cucumber supplementation, particularly with standardized extracts rich in frondosides, is becoming more accessible thanks to Primary Nutrition Inc and it’s Oceanicare product line. For clinicians considering natural, adjunctive options in patient care, frondoside-rich extracts may serve as valuable additions, especially for patients seeking natural therapies in support of immune health or inflammation management.
Conclusion
As we continue to investigate the multifaceted benefits of sea cucumbers and their bioactive components, it is essential to approach these findings with a scientific lens. This curated collection of reports aims to facilitate further discussion and research in the field, supporting healthcare professionals in exploring innovative strategies for patient wellness. We encourage you to review the attached data and reach out for further discussion or questions on the applications of sea cucumber extracts in clinical practice.
For Further Reading
Included with this document are selected studies and reviews detailing the pharmacological properties of Frondosides and their implications in health. We encourage an open dialogue on the integration of these findings into clinical practice.
Oceanicure™ SC-23P™ is available at a growing list of independant and compound pharmacies. Our product is offered via physician and healthcare professional recommendation and typically available behind the counter. So, please kindly write a prescription or recommendation if you feel this product may be helpful to your patients or clients. We also welcome heathcare practicioners who manage their own dispensaries. Send us an email for dealer pricing and initial qualifying MOQ.
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